| 131 | 6 | 48 |
| 下载次数 | 被引频次 | 阅读次数 |
目的：观察槐榆清热止血方对混合痔患者外剥内扎术后不适症状及创面恢复情况的影响。方法：选取行外剥内扎手术的混合痔患者100例，按随机数字表法分为对照组和观察组各50例。两组术后均每日进行常规换药和坐浴，观察组在此基础上加服槐榆清热止血方，两组均以7 d为1个疗程，共治疗2个疗程。比较两组患者术后1 d、3 d、7 d、14 d的伤口疼痛、肛门坠胀、伤口出血、创面水肿、创面渗出量化分级评分，以及伤口愈合时间。结果：与对照组比较，观察组术后3 d、7 d、14 d的伤口疼痛、肛门坠胀、术后出血程度更轻，术后7 d、14 d的创面水肿、创面渗出程度更轻，且术后伤口愈合时间更短，差异均有统计学意义（P<0.05）。结论：槐榆清热止血方能缓解混合痔外剥内扎术后不适症状，促进创面恢复。
Abstract：Objective:To observe the effect of Huaiyu Qingre Zhixue Formula （槐榆清热止血方 ） on the uncomfortable symptoms and wound recovery of patients with mixed hemorrhoids after Milligan-Morgan surgery. Methods:A total of 100 patients with mixed hemorrhoids who underwent Milligan-Morgan surgery were divided into control group and observation group according to the random number table method,with50 cases in each group. After the surgery,patients in the control group were given conventional dressing change and sitz bath every day,and the patients in the observation group were given oral administration of Huaiyu Qingre Zhixue Formula on the basis of the control group. The two groups all took 7 days as a course of treatment and were treated for 2 courses. The quantified and classified scores of wound pain,anal distension,wound bleeding,wound edema,and wound exudation at 1 day,3 days,7 days and 14 days after the surgery were compared between the two groups.In addition,the wound healing time of the two groups was recorded and compared. Results:Three days,7 days and 14 days after the surgery,the degree of wound pain,anal distension,and wound bleeding of the patients in the observation group were lighter than that of the patients in the control group(P<0.05). Seven days and 14 days after the surgery,the degree of wound edema and wound exudation of the patients in the observation group were lighter than that of the patients in the control group(P<0.05).The wound healing time of the observation group was shorter than that of the control group(P <0.05).Conclusions:For patients with mixed hemorrhoids after Milligan-Morgan surgery,Huaiyu Qingre Zhixue Formula can relieve the uncomfortable symptoms and promote the wound recovery.
[1]李军来.手术治疗痔疮临床疗效及发病相关因素分析[J].临床医药文献电子杂志，2017,15(23):134-135.
[2]乔敬华，何佳伟，周军惠.基于流行病学调查的农村社区居民痔病中医药防治对策探讨[J].上海中医药杂志，2019,53(6):14-19.
[3]中国中西医结合学会大肠肛门病专业委员会.中国痔病诊疗指南（2020）[J].结直肠肛门外科，2020,26(5):519-533.
[4]周清，陶晓春，王琛.痔外剥内扎术后常见并发症防治的中西医研究进展[J].陕西中医，2019,40(4):540-542.
[5]步宏，李一雷.病理学[M]. 9版.北京：人民卫生出版社，2018:65-68.
[6]陈孝平，汪建平.外科学[M]. 8版.北京：人民卫生出版社，2013:103-104.
[7]陈洁.加味槐花散治疗湿热下注型混合痔术后并发症的临床观察[D].福州：福建中医药大学，2020.
[8]贾佼佼，苗明三．槐花的化学、药理及其临床应用[J].中医学报，2014,29(5):714-717,745.
[9]张向阳，魏红，郑海萍，等.地榆炭的研究进展[J].环球中医药，2014,7(2):158-160.
[10]张俊飞，孙广璐，张彬，等.侧柏叶药理作用的研究进展[J].时珍国医国药，2013,24(9):2231-2233.
[11]孟宁，黄山，胡丹丹，等.藏荆芥不同萃取部位抗炎、镇痛活性研究[J].中华中医药学刊，2018,36(8):1874-1877.
[12]李嘉诚，吴岚，蔡同凯，等.黄柏化学成分及其药理作用研究进展[J].药学实践杂志，2018,36(5):389-391,398.
[13]钟赣生.中药学[M].北京：中国中医药出版社，2016:356-357.
[14]朱亚南，杨七妹，张硕，等.黄芩苷与黄芩素药理作用及机制研究进展[J].时珍国医国药，2020,31(4):921-925.
[15] LI J,WU Y T,ZHANG S,et al. Baicalein protect pancreatic injury in rats with severe acute pancreatitis by inhibiting pro-inflammatory cytokines expression[J]. Biochem Bioph Res Co,2015,466(4):664.
[16]卜妍红，陆婷，吴虹，等.栀子化学成分及药理作用研究进展[J].安徽中医药大学学报，2020,39(6):89-93.
[17]万亮琴，张子剑，谭琰，等.栀子及栀子苷抗炎作用机制的最新研究进展[J].现代中药研究与实践，2017,31(3):80-83.
[18]赵静，夏晓培.当归的化学成分及药理作用研究现状[J].临床合理用药杂志，2020,13(6):172-174.
[19]骆亚莉，李应东，刘永琦，等.当归有效成分对冷应激小鼠抗氧化功能影响[J].中国公共卫生，2014,30(5):607-609.
[20]陈金鹏，张克霞，刘毅，等.地黄化学成分和药理作用的研究进展[J].中草药，2021,52(6):1772-1784.
[21]郑莹，王帅，孟宪生，等.中药枳壳挥发油成分气相色谱-质谱联用分析和促进胃肠动力药效研究[J].时珍国医国药，2015,26(3):516-518.
基本信息:
DOI：10.16295/j.cnki.0257-358x.2023.03.009
中图分类号:R266
引用信息:
[1]许杰.槐榆清热止血方在混合痔外剥内扎术后的应用效果研究[J],2023,42(03):250-254.DOI:10.16295/j.cnki.0257-358x.2023.03.009.