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回顾性分析北京中医药大学东直门医院收治的1例伊布替尼治疗慢性淋巴细胞白血病致肺部感染患者的临床资料，并复习相关文献。该患者在服用伊布替尼治疗时并发肺部感染，遂停药，结合中医药治疗后感染症状得到控制，后继续坚持口服中药治疗，慢性淋巴细胞白血病的相关症状得到改善，且未再发生感染。针对长时间应用伊布替尼治疗慢性淋巴细胞白血病的患者，需警惕肺部真菌感染的发生。中医药在治疗慢性淋巴细胞白血病中，能够防止各类感染的发生，提高机体耐受力，延长患者生存期。
Abstract：The clinical data of a patient with pulmonary infection caused by chronic lymphocytic leukemia treated with ibrutinib in Dongzhimen Hospital of Beijing University of Chinese Medicine were retrospectively analyzed,and the relevant literature was reviewed. The patient was complicated with pulmonary infection during ibrutinib treatment,so ibrutinib was stopped and traditional Chinese medicine treatment was combined,and the infection symptoms were controlled. After continued to adhere to oral traditional Chinese medicine treatment,the symptoms related to chronic lymphocytic leukemia were relieved,and there was no recurrence of infection. For patients with chronic lymphocytic leukemia treated with ibrutinib for a long period of time,it is necessary to be alert to the occurrence of pulmonary fungal infection. Traditional Chinese medicine can prevent the occurrence of various infections,improve the body tolerance,prolong the survival of patients in the treatment of chronic lymphocytic leukemia.
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基本信息:
DOI：10.16295/j.cnki.0257-358x.2024.09.019
中图分类号:R273
引用信息:
[1]田文灏,马薇,何晓玉,等.中医药治疗慢性淋巴细胞白血病及伊布替尼不良反应个案报道[J].山东中医杂志,2024,43(09):1024-1030.DOI:10.16295/j.cnki.0257-358x.2024.09.019.
基金信息:
中华中医药学会血液病分会血液病优势病种相关基础实验研究（编号：202169-004）
2024-09-05
2024-09-05