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中医“天人合一”观与现代生态学理论均强调人体内环境的稳定和人与自然的和谐统一。肠道微生态既是人体最大的内部生态环境，也是自然界的一部分，人与微生物之间和谐相处才能保持机体的正常运转，这与中医“天人合一观”相契合。肠道微生态的形成和发展依靠人的先后天功能，且肠道微生态的改变能够在人体功能上具象化，二者同构相依；天人相应的微观基础是“气”，“气”与肠道微生物具有相似的功能学特性，二者同气相求；象思维则可为探索肠道微生态与各脏腑之间的联系提供理论指导，二者同象相依；肠道生态环境中亦存在着暗含生理病理规则的节律，二者同律相应。文章深入剖析肠道微生态与中医“天人合一”观的相关性，并总结归纳肠道微生态的时空特异性，希望能为找寻阐释个体疾病发生发展规律的潜在生物标志物提供帮助，也为探索改善人体生命质量的微生态疗法提供理论依据。
Abstract：The concept of “the unity between man and nature” contained in traditional Chinese medicine(TCM) is closely related to ecological theory,both of which emphasize the stability of the internal environment of the human body and the harmony and unity between man and nature. The intestinal microecology is not only the largest internal ecological environment of the human body but also a part of nature. Only when humans and microorganisms coexist in harmony can the normal operation of the body be maintained,which is in line with the TCM concept of “the unity between man and nature”. The formation and development of the intestinal microecology rely on both innate and acquired human functions. Moreover,changes in the intestinal microecology can affect human functions,and the two are isomorphic and interdependent. The microscopic basis of the correspondence between man and nature is “qi”. “Qi” and the intestinal microecology share similar functional characteristics,and they are attracted to each other due to their similar natures. The image-based thinking can provide theoretical guidance for exploring the relationship between the intestinal microecology and various internal organs,as humans and nature are interdependent and share the same image. The intestinal ecosystem also has rhythms that follow physiological and pathological patterns,as humans and nature share the same rhythm. The article deeply analyzes the correlation between intestinal microecology and the TCM concept of “the unity between man and nature”,and summarizes the spatiotemporal specificity of intestinal microecology. It is hoped that this will help identify potential biomarkers for elucidating the patterns of disease occurrence and development,and also provide a theoretical basis for exploring microbiota-based therapies to improve the quality of human life.
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基本信息:
DOI：10.16295/j.cnki.0257-358x.2025.09.008
中图分类号:R22
引用信息:
[1]王礼宁,李晓月,李丽秋,等.从中医“天人合一”观剖析肠道微生态内涵[J].山东中医杂志,2025,44(09):975-981.DOI:10.16295/j.cnki.0257-358x.2025.09.008.
基金信息:
国家自然科学基金面上项目(编号：81973885); 江苏高校优势学科(中西医结合)建设工程资助项目(批文号：苏政办发[2018]87号); 江苏省中医药科技发展计划面上项目(编号：MS2021044); 江苏高校中西医临床医学品牌专业建设工程资助项目(二期)(编号：2020PPZXL26); 国家中医药管理局高水平中医药重点学科-中医骨伤科学项目
2025-09-05
2025-09-05