目的：观察基于六经辨证方法治疗多重耐药菌（MDRO）肺部感染的临床疗效，为治疗该病提供中医辨证治疗思路。方法：选取2020—2021年广州市番禺区中医院呼吸与危重症医学科、重症医学科诊断为MDRO肺部感染的70例患者为研究对象，采用随机数字表法分为治疗组、对照组。对照组根据病原体类型选择相应药物抗感染治疗，治疗组在对照组基础上联合六经辨证治疗。以炎症指标（白细胞、降钙素原、C反应蛋白）、肺炎严重程度指数、细菌清除率、氧合指数、退热时间及住院天数作为疗效指标，观察两组患者治疗效果。结果：治疗后，治疗组总有效率高于对照组，肺炎严重程度指数评分低于对照组（P<0.05）；在炎症指标方面治疗组低于对照组，两组比较差异有统计学意义（P<0.05）；治疗组细菌清除率高于对照组（P<0.05）；两组患者氧合指数水平比较治疗组显著高于对照组，差异有统计学意义（P<0.01）；治疗组退热时间及住院天数明显低于对照组（P<0.01）。结论：对MDRO肺部感染患者进行六经辨证诊治可获得较好的临床疗效，降低病情严重程度，降低炎症水平，提高细菌清除率，改善氧合指数，值得临床推广。

Objective:To observe the clinical effect of the treatment of multidrug resostant organism(MDRO) pulmonary infection based on the six channels syndrome differentiation method,and to provide traditional Chinese medicine(TCM) syndrome differentiation and treatment ideas for this disease.Methods:A total of 70 patients diagnosed as MDRO pulmonary infection in the Department of Respiratory and Critical Care Medicine and the Department of Critical Care Medicine of Panyu District Hospital of Traditional Chinese Medicine of Guangzhou from 2020 to 2021 were collected as the study subjects,and were divided into the treatment group and the control group by random number table method. The control group was treated by corresponding drugs for anti infection according to the type of pathogens,and the treatment group was combined with syndrome differentiation of six channels on the basis of the treatment of the control group. Inflammatory indicators(leukocyte,procalcitonin,C-reactive protein),pneumonia severity index,bacterial clearance rate,oxygenation index,duration of fever reduction and hospital stay were used as therapeutic indicators to observe the therapeutic effect of the two groups. Results:After treatment,the total effective rate of the treatment group was higher than that of the control group,and the score of pneumonia severity index of the treatment group was lower than that of the control group(P<0.05). In terms of inflammation indexes,there was statistical difference between the two groups,and the treatment group was lower than the control group(P<0.05).The bacterial clearance rate in the treatment group was higher than that in the control group(P<0.05).There was statistical difference in oxygenation index between the two groups,and the treatment group was significantly higher than the control group(P<0.01). The duration of fever and hospitalization in the treatment group were significantly lower than those in the control group(P<0.01). Conclusions:The six channels syndrome differentiation and treatment of MDRO patients with pulmonary infection can obtain better clinical effect,reduce the severity of the disease,reduce the level of inflammation,increase the bacterial clearance rate,and improve the oxygenation index,which is worthy of clinical promotion.