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目的:评估非小细胞肺癌胸腔镜下肺切除术后咳嗽患者的咳嗽程度,探讨非小细胞肺癌胸腔镜下肺切除术后咳嗽中医证型分布特点及其影响因素。方法:对315例非小细胞肺癌胸腔镜下肺切除术后咳嗽患者进行问卷调查,收集患者基本信息、手术资料、中医四诊信息,并评估患者术后咳嗽程度。根据咳嗽中医辨证标准进行证型判定,分析肺癌术后咳嗽中医证型分布规律并探究其影响因素。结果:315例患者术后咳嗽中医证型出现频率由高到低依次为:风盛挛急证(39.68%)>气阴两虚证(30.16%)>肺气亏虚证(14.29%)>肺阴亏虚证(12.06%)>痰湿蕴肺证(2.54%)>痰热郁肺证(1.27%)。315名患者中文版莱斯特咳嗽量表(LCQ-MC)生理维度得分(4.68±1.21)分,心理维度得分(5.10±1.12)分,社会维度得分(5.78±1.02)分,总分(15.79±3.30)分;咳嗽数字分级法评估量表(NRS)得分(3.30±2.05)分。4种主要中医证型分布与年龄、手术侧、术中出血量、是否进行系统淋巴结清扫、病理类型、病理分期的相关性无统计学意义(P>0.05)。4种主要中医证型分布与性别、吸烟史、手术时长、手术范围相关,差异有统计学意义(P<0.05)。结论:非小细胞肺癌胸腔镜下肺切除术后咳嗽中医证型以风盛挛急证为主,其次是气阴两虚证、肺气亏虚证、肺阴亏虚证,痰湿蕴肺证和痰热郁肺证出现较少。证型与性别、吸烟史、手术时长、手术范围有关。术后咳嗽患者多为轻中度咳嗽。
Abstract:Objective:To evaluate the degree of cough in patients with non-small cell lung cancer after thoracoscopic pneumonectomy,and to explore the distribution characteristics and influencing factors of traditional Chinese medicine syndrome types of cough after thoracoscopic pneumonectomy of non-small cell lung cancer. Methods:A questionnaire survey was conducted on 315 patients with cough after thoracoscopic pneumonectomy with non-small cell lung cancer. The basic information,surgical data and four TCM diagnostic information of the patients were collected,and the degree of postoperative cough of the patients was assessed. According to the standard of TCM syndrome differentiation of cough,the distribution of TCM syndrome of cough after lung cancer surgery was analyzed and its influencing factors were explored.Results:In 315 patients with postoperative cough,the frequency of TCM syndrome from high to low was as follows:excessive and repetitive wind syndrome(39.68%) > qi-yin deficiency syndrome(30.16%) > lung qi deficiency syndrome(14.29%) > lung yin deficiency syndrome(12.06%) > phlegm-dampness accumulation in lung syndrome(2.54%) > phlegm-heat stagnation in lung syndrome(1.27%). In 315 patients,LCQ-MC scores were 4.68±1.21 in physiological dimension,5.10±1.12 in psychological dimension and 5.78±1.02 in social dimension,the total score was 15.79±3.30. NRS score was 3.30±2.05. There was no statistical significance in the distribution of the four main TCM syndrome types and age,surgical side,intraoperative blood loss,whether systematic lymph node dissection was performed,pathological type and pathological stage(P>0.05).The distribution of the four main TCM syndrome types was related to significance with gender,smoking history,operation duration and operation scope,the difference was statistically significant(P<0.05). Conclusions:The TCM syndrome of cough after thoroscopic pneumonectomy of non-small cell lung cancer is mainly excessive and repetitive wind syndrome,and it is followed by qi-yin deficiency syndrome,lung qi deficiency syndrome,lung yin deficiency syndrome,and phlegm-dampness accumulation in lung syndrome and phlegm-heat stagnation in lung syndrome. The syndrome type was retaled to gender,smoking histroy,surgical duration and surgical scope. Postoperative cough patients mostly suffer from mild to moderate cough.
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基本信息:
DOI:10.16295/j.cnki.0257-358x.2024.12.010
中图分类号:R273
引用信息:
[1]张笑雪,周玲羚,徐嵩,等.非小细胞肺癌胸腔镜下肺切除术后咳嗽中医证型分布及其影响因素[J].山东中医杂志,2024,43(12):1373-1379.DOI:10.16295/j.cnki.0257-358x.2024.12.010.
基金信息:
天津市中医药重点领域科研项目(编号:2022010); 天津市高等学校创新团队培养计划项目(编号:TD13-5051); 天津市卫生与健康委员会十二五特色学科(编号:20200402)
2024-06-02
2024
2024-07-08
2024
1
2024-12-05
2024-12-05